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Understanding Antibiotic Resistance and Its Implications

This quiz tests knowledge on antibiotic resistance, its mechanisms, and implications for treatment and public health.

1 [43] Antibiotic resistance is exchanged between different bacteria by ________ that carry genes which encode antibiotic resistance which may result in co-resistance to multiple antibiotics.

2 Mechanisms for freeing iron from the body (such as toxins and ________) are common among pathogens.

3 ________ are a commonly suggested method for combating MDRO infections.

4 Inappropriate antibiotic treatment and ________ have been a contributing factor to the emergence of resistant bacteria.

5 ________ are another alternative that goes beyond traditional antibiotics by employing a live culture which may in theory establish itself as a symbiont, competing, inhibiting, or simply interfering with colonization by pathogens.

6 [30][31] Interaction with the combined oral contraceptive pill through induction of hepatic enzymes by the antifungal medication griseofulvin and the broad-spectrum antibiotic ________ has been shown to occur.

7 [2] This original definition excluded naturally occurring substances that kill bacteria but are not produced by microorganisms (such as gastric juice and ________) and also excluded synthetic antibacterial compounds such as the sulfonamides.

8 The restriction of ________ availability is one way the human body limits bacterial proliferation [74].

9 [14] However, his work went by without much notice from the scientific community until ________'s discovery of Penicillin in 1928.

10 [1] Antibiotics belong to the broader group of ________ compounds, used to treat infections caused by microorganisms, including fungi and protozoa.

💡 Interesting Facts

  • some pulvinones have shown anticoagulant activity in rats, whilst other pulvinone derivatives are patented antibiotics for use in animals.
  • the giant leucopax mushroom has bioactive compounds with antioxidative, antibiotic, and anti-cancer properties.
  • worldwide resistance to the antibiotic mecillinam is remarkably low, even though it has been widely used as a treatment for urinary tract infections since the 1970s.
  • one bacterial strain of Streptomyces griseus has the capacity to produce up to 34 different secondary metabolites including antibiotics.
  • shrimp farms are a serious threat to the environment because they cause widespread destruction of mangroves and disperse antibiotics through their wastewater.
  • ceftaroline is a novel antibiotic against MRSA and other resistant bacterial strains and is under clinical trial as a treatment for infectious diseases such as community-acquired pneumonia.
  • Elizabeth Lee Hazen developed the world's first useful antifungal antibiotic, nystatin.
  • Ernest Duchesne discovered penicillin's antibiotic powers 32 years before Alexander Fleming.
  • cefquinome is an antibiotic developed to treat bovine respiratory disease.