Understanding Chemotherapy and Its Mechanisms Quiz - Test Your Knowledge

targeted therapy is a type of chemotherapy which blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth.

halomon (chemical structure pictured), a natural halogenated organic compound isolated from red algae, shows early preclinical promise as a potential antitumor agent.

synthetic analogues of camptothecin, a cytotoxic quinoline alkaloid isolated from the Chinese tree Camptotheca acuminata, are being used as anti-cancer drugs.

the edible fungus Polyozellus multiplex (pictured) has attracted research interest as a possible chemopreventative agent against stomach cancer.

the first registered clinical use of an NK1 receptor blocker was the treatment of nausea and vomiting induced by chemotherapy.

the most recent of the six different methods of total synthesis of the anti-cancer drug paclitaxel, a drug originally derived from the rare Pacific Yew, was developed at the Tokyo University of Science in 1999.

drug-eluting stents are often coated with chemotherapy compounds, to prevent blockage by tissue when placed into arteries.

DirectHit is the only accurate pharmacodiagnostic test to determine possible treatment outcomes of anticancer chemotherapy drugs for breast cancer.

5-HT3 antagonists, effective for treating the nausea and vomiting due to chemotherapy, have no effect on motion sickness.

Mdm2, whose role in regulating p53 was discovered by British scientist Karen Vousden, is a potential target for anti-cancer drugs.

Body surface area is an important measure used in medicine to calculate chemotherapy dosage.

body surface area is an important measure used in medicine to calculate chemotherapy dosage.

Bubba the Grouper, the first known fish to receive chemotherapy, died recently in Chicago, Illinois.

Japanese scientists have found anticancer activity in some Brazilian traditional remedies.

Understanding Chemotherapy and Its Mechanisms

1 Solutions to this problem include ________ (both brachytherapy and teletherapy) and surgery.

2 The CTZ is in the ________, outside the blood-brain barrier, and is thus susceptible to stimulation by substances present in the blood or cerebral spinal fluid.

3 Specific chemotherapeutic agents are associated with organ-specific toxicities, including ________ (e.g., doxorubicin), interstitial lung disease (e.g., bleomycin) and occasionally secondary neoplasm (e.g., MOPP therapy for Hodgkin's disease).

4 Vinca alkaloids bind to specific sites on tubulin, inhibiting the assembly of tubulin into microtubules (________ of the cell cycle).

5 A granisetron ________ (Sancuso) was approved by the FDA in September 2008.

6 Self-care measures, such as eating frequent small meals and drinking clear liquids or ________ tea, are often recommended.

7 Medications that kill rapidly dividing cells or blood cells are likely to reduce the number of ________ in the blood, which can result in bruises and bleeding.

8 lymphoid: ________ (Ibritumomab, Ofatumumab, Rituximab, Tositumomab), CD52 (Alemtuzumab)

9 This means that other fast-dividing cells, such as those responsible for hair growth and for replacement of the intestinal ________ (lining), are also often affected.

10 ________ is the uncontrolled growth of cells coupled with malignant behavior: invasion and metastasis.

💡 Interesting Facts

Related Quizzes

Understanding Cancer: A Comprehensive Quiz

Understanding HIV: Knowledge Quiz

Exploring the Evolution of Hospitals

Understanding Hypertension: A Comprehensive Quiz